Architect the whole offering around "we deliver value without ever touching your proprietary data." Pre-screening models on public + Matter Loop wet-lab data → ranked candidate set → customer's internal team validates against their data.
The thesis breaks the moment you realize: the data belongs to the customer, not the startup. BASF doesn't buy from startups; they partner with academia and keep data internal. Customer keeps data → vendor flywheel never spins.
Matter Loop should: take target spec + constraints from customer → return a ranked candidate set with synthesizability + qualification-path scores → customer's internal team validates against their data.